Selected article for: "randomized trial and significant improvement"

Author: Stoecker, Allison; Lear, William; Johnson, Karsten; Bahm, Jared; Kruzic, Jamie J.
Title: Enhanced perfusion of elliptical wound closures using a novel adhesive suture retention device
  • Cord-id: qzurzhp8
  • Document date: 2021_9_14
  • ID: qzurzhp8
    Snippet: BACKGROUND AND AIMS: The purpose of this investigation was to test the hypothesis that a novel adhesive retention suture device (ARSD) can increase perfusion at elliptical wound closures by distributing stress away from the suture site. METHODS: Stress in the skin around a suture both with and without support from an ARSD was evaluated using a finite element model. A single‐center, randomized split‐scar comparison trial using laser speckle contrast analysis was used to quantify the perfusion
    Document: BACKGROUND AND AIMS: The purpose of this investigation was to test the hypothesis that a novel adhesive retention suture device (ARSD) can increase perfusion at elliptical wound closures by distributing stress away from the suture site. METHODS: Stress in the skin around a suture both with and without support from an ARSD was evaluated using a finite element model. A single‐center, randomized split‐scar comparison trial using laser speckle contrast analysis was used to quantify the perfusion at elliptical wound closures in human patients both with and without an ARSD. RESULTS: The finite element model revealed that the ARSD promoted load transfer to the skin over a larger area, thus reducing the local stress and deformation in the skin around the suture site. Results from the split‐scar study showed a mean improvement of 25% perfusion units with the ARSD, and the improvement was statistically significant (p = 0.002). CONCLUSION: The reduction in local stress and enhanced perfusion around the suture site reveals the potential benefit of using an ARSD to enable more efficient healing by avoiding complications associated with both low perfusion and skin tearing, such as dehiscence, infection, and cheese wiring.

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