Author: Amanda D. Melin; Mareike C. Janiak; Frank Marrone; Paramjit S. Arora; James P. Higham
Title: Comparative ACE2 variation and primate COVID-19 risk Document date: 2020_4_11
ID: bieqw3x1_4
Snippet: We compiled ACE2 gene sequence data from 27 primate species for which genomes are publicly available, covering primate taxonomic breadth. For comparison, we assessed 4 species of other mammals that have been tested directly for SARS-CoV2 susceptibility in laboratory infection studies 22 . We also included in our analysis the amino acid sequence variation at these sites for horseshoe bats, thought to be the original vector of the virus, and pangol.....
Document: We compiled ACE2 gene sequence data from 27 primate species for which genomes are publicly available, covering primate taxonomic breadth. For comparison, we assessed 4 species of other mammals that have been tested directly for SARS-CoV2 susceptibility in laboratory infection studies 22 . We also included in our analysis the amino acid sequence variation at these sites for horseshoe bats, thought to be the original vector of the virus, and pangolins, a potential intermediate host, where viral recombination may have led to the novel viral form SARS-CoV-2 23 .
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