Selected article for: "positive control and untreated control"
Author: Nicola F Fletcher; Luke W Meredith; Emma L Tidswell; Steven R Bryden; Daniel Gonçalves-Carneiro; Yasmin Chaudhry; Claire Shannon-Lowe; Michael A Folan; Daniella A Lefteri; Marieke Pingen; Dalan Bailey; Clive S McKimmie; Alan W Baird
Title: A novel antiviral formulation inhibits a range of enveloped viruses.
  • Document date: 2020_3_30
    • ID: nly9vojr_88
    Snippet: The copyright holder for this preprint (which was not peer-reviewed) is . https://doi.org/10.1101/2020.03.29.009464 doi: bioRxiv preprint compared with control treated virus. (B) VSV-G pseudovirus was treated with 2% ViroSAL or the equivalent concentrations of caprylate, DPPG, Lecithin and Kolliphor for 2 minutes, and then pH restored to 7. To control for the effect of pH on viral infectivity, virus was treated with a pH5.5 buffer, equivalent to .....
    Document: The copyright holder for this preprint (which was not peer-reviewed) is . https://doi.org/10.1101/2020.03.29.009464 doi: bioRxiv preprint compared with control treated virus. (B) VSV-G pseudovirus was treated with 2% ViroSAL or the equivalent concentrations of caprylate, DPPG, Lecithin and Kolliphor for 2 minutes, and then pH restored to 7. To control for the effect of pH on viral infectivity, virus was treated with a pH5.5 buffer, equivalent to that of ViroSAL, for 2 minutes and then the pH of the virus was restored to 7. 10ng/ml IFN-y was included as a positive antiviral control. Data are presented as mean infectivity ± SD relative to the untreated virus control (n = 3 independent experiments). ***P < 0.001, **P < 0.01, ns: not significant.

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