Author: Longxian Lv; Gaolei Li; Jinhui Chen; Xinle Liang; Yudong Li
Title: Comparative genomic analysis revealed specific mutation pattern between human coronavirus SARS-CoV-2 and Bat-SARSr-CoV RaTG13 Document date: 2020_3_2
ID: 3h1o0oz3_8
Snippet: Genome sequences were aligned using MUSCLE v3.8.31 (9), followed by manual adjustment using BioEdit v7.2.5. Phylogenetic analyses of complete genome were performed using maximum-likelihood method and general time-reversible model of nucleotide substitution with gamma-distributed rates among sites (GTR+G) in RAxML v8.1.21 (10) . Support for the inferred relationships was evaluated by a bootstrap analysis with 1000 replicates and trees were rooted .....
Document: Genome sequences were aligned using MUSCLE v3.8.31 (9), followed by manual adjustment using BioEdit v7.2.5. Phylogenetic analyses of complete genome were performed using maximum-likelihood method and general time-reversible model of nucleotide substitution with gamma-distributed rates among sites (GTR+G) in RAxML v8.1.21 (10) . Support for the inferred relationships was evaluated by a bootstrap analysis with 1000 replicates and trees were rooted with the alpha-coronavirus lineage as an outgroup. The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.02.27.969006 doi: bioRxiv preprint
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