Author: Michael Jay Corley; Christopher Sugai; Michael Schotsaert; Robert E. Schwartz; Lishomwa C Ndhlovu
Title: Comparative in vitro transcriptomic analyses of COVID-19 candidate therapy hydroxychloroquine suggest limited immunomodulatory evidence of SARS-CoV-2 host response genes. Document date: 2020_4_14
ID: 30x26ip7_19
Snippet: Hence, we examined transcriptional differences in human primary CD14+ monocyte MCSF-differentiated macrophage conditions treated with HCQ for 24 hours (Supplemental Table 1 ). Differential gene expression analyses showed that 159 genes were differentially expressed comparing the untreated and HCQ treated conditions corrected for multiple comparisons using the FDR method at P < 0.05 (Supplemental Data 1)......
Document: Hence, we examined transcriptional differences in human primary CD14+ monocyte MCSF-differentiated macrophage conditions treated with HCQ for 24 hours (Supplemental Table 1 ). Differential gene expression analyses showed that 159 genes were differentially expressed comparing the untreated and HCQ treated conditions corrected for multiple comparisons using the FDR method at P < 0.05 (Supplemental Data 1).
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