Future Directions for Dementia Risk Reduction and Prevention Research: An International Research Network on Dementia Prevention Consensus

Anstey, Kaarin J.; Peters, Ruth; Zheng, Lidan; Barnes, Deborah E.; Brayne, Carol; Brodaty, Henry; Chalmers, John; Clare, Linda; Dixon, Roger A.; Dodge, Hiroko; Lautenschlager, Nicola T.; Middleton, Laura E.; Qiu, Chengxuan; Rees, Glenn; Shahar, Suzana; Yaffe, Kristine

In the past decade a large body of evidence has accumulated on risk factors for dementia, primarily from Europe and North America. Drawing on recent integrative reviews and a consensus workshop, the International Research Network on Dementia Prevention developed a consensus statement on priorities for future research. Significant gaps in geographical location, representativeness, diversity, duration, mechanisms, and research on combinations of risk factors were identified. Future research to inform dementia risk reduction should fill gaps in the evidence base, take a life-course, multi-domain approach, and inform population health approaches that improve the brain-health of whole communities.