Author: Bloom, Patricia P; Chung, Raymond T
Title: In reply to Drs. Lv, Yang, and Deng. Cord-id: o5qh86ie Document date: 2020_8_7
ID: o5qh86ie
Snippet: We respectfully disagree with your interpretation of the lag in serum alanine aminotransferase (ALT) elevations behind aspartate aminotransferase (AST) elevations in patients with COVID-19. Specifically, you suggest that this lag reflects a dissociation between ALT and AST elevations and therefore implies a non-hepatic source of AST elevation.
Document: We respectfully disagree with your interpretation of the lag in serum alanine aminotransferase (ALT) elevations behind aspartate aminotransferase (AST) elevations in patients with COVID-19. Specifically, you suggest that this lag reflects a dissociation between ALT and AST elevations and therefore implies a non-hepatic source of AST elevation.
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