Author: Ting Gao; Mingdong Hu; Xiaopeng Zhang; Hongzhen Li; Lin Zhu; Hainan Liu; Qincai Dong; Zhang Zhang; Zhongyi Wang; Yong Hu; Yangbo Fu; Yanwen Jin; Kaitong Li; Songtao Zhao; Yongjiu Xiao; Shuping Luo; Lufeng Li; Lingfang Zhao; Junli Liu; Huailong Zhao; Yue Liu; Weihong Yang; Jing Peng; Xiaoyu Chen; Ping Li; Yaoning Liu; Yonghong Xie; Jibo Song; Lu Zhang; Qingjun Ma; Xiuwu Bian; Wei Chen; Xuan Liu; Qing Mao; Cheng Cao
Title: Highly pathogenic coronavirus N protein aggravates lung injury by MASP-2-mediated complement over-activation Document date: 2020_3_30
ID: dxs8ggyh_13
Snippet: The copyright holder for this preprint (which was not peer-reviewed) is . https://doi.org/10.1101/2020.03. 29.20041962 doi: medRxiv preprint CoV N but not negative control animals (Fig. S3A) . These results confirmed an in situ direct binding and activation of MASP-2 by SARS-CoV N in mice lung tissue......
Document: The copyright holder for this preprint (which was not peer-reviewed) is . https://doi.org/10.1101/2020.03. 29.20041962 doi: medRxiv preprint CoV N but not negative control animals (Fig. S3A) . These results confirmed an in situ direct binding and activation of MASP-2 by SARS-CoV N in mice lung tissue.
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