Remote screening of diabetic retinopathy using ultra-widefield retinal imaging.

Kato, Aki; Fujishima, Keiichiro; Takami, Kazuhisa; Inoue, Naomi; Takase, Noriaki; Suzuki, Norihiro; Suzuki, Katsuya; Kuwayama, Soichiro; Yamada, Akiko; Sakai, Katsuo; Hotta, Ryosuke; Nozaki, Miho; Yoshida, Munenori; Hirano, Yoshio; Yasukawa, Tsutomu; Ogura, Yuichiro

AIMS To study the possibility of constructing a remote interpretation system for retinal images. METHODS An ultra-widefield (UWF) retinal imaging device was installed in the internal medicine department specializing in diabetes to obtain fundus images of patients with diabetes. Remote interpretation was conducted at Nagoya City University using a cloud server. The medical data, severity of retinopathy, and frequency of ophthalmologic visits were analyzed. RESULTS Four hundred ninety-nine patients (mean age, 62.5 ± 13.4 years) were included. The duration of diabetes in 240 (48.1%) patients was less than 10 years and 433 (86.7%) patients had a hemoglobin (Hb) A1c below 8%. Regarding the retinopathy severity, 359 (72.1%) patients had no diabetic retinopathy (NDR), 63 (12.6%) mild nonproliferative retinopathy (NPDR), 37 (7.6%) moderate NPDR, 13 (2.6%) severe NPDR, and 27 (5.0%) PDR. Two hundred forty-one (48.3%) patients had an ophthalmologic consultation within 1 year, 104 (20.8%) had no history of an ophthalmologic consultation. DR was not present in 86 (82.7%) patients who had never had an ophthalmologic examination, 32 (80.0%) patients with severe NPDR or PDR had had an ophthalmologic visit within 1 year. The frequency of ophthalmic visits was correlated negatively with age, diabetes duration, HbA1c, and severity of retinopathy. CONCLUSION Remote interpretation of DR using UWF retinal imaging was useful for retinopathy screening. During the COVID-19 pandemic, a remote screening system that can ensure compulsory social distancing and reduce the number of ophthalmic visits can be a safe system for patients and clinicians.