Author: Vazquez, Rafael Ricardo Valdez; Gallardo-Rincón, Héctor; LomelÃn-Gascon, Julieta; Ville Benavides, Rodrigo; Juárez, Linda Morales; Bello, Héctor Herrera; Castañeda, Lidia Moreno; Chavarria, Adrian Palacios; Castillo, Pablo Escalera; Gonzalez, Luis Esteban Ramirez; Avendaño, Mónica Arboleya; Berlanga, Santiago Treviño; Loza, Reyna Albertina Rosas; Wyssmann, Renate Victoria Ãlvarez; Lezama, Erika Salinas; Romero, Alonso Gutiérrez; Ortega, MarÃa Dolores Niembro; Acosta, Liudmila Villegas; Schotman, Ailyn Cendejas; Montoya, Jennifer Bertin; Rodriguez, Andrea Gonzalez; Ramos, Laura MarÃa Badel; Martinez-Juarez, Luis Alberto; Saucedo-MartÃnez, Rodrigo; Montoya, Alejandra; Tapia-Conyer, Roberto
Title: Impact of preemptive hospitalization on health outcomes at the temporary COVID-19 hospital in Mexico City: a prospective observational study Cord-id: bg7w7k1k Document date: 2021_8_27
ID: bg7w7k1k
Snippet: INTRODUCTION: In response to the evolution of the coronavirus disease 2019 (COVID-19) pandemic, the admission protocol for the temporary COVID-19 hospital in Mexico City has been updated to hospitalize patients preemptively with an oxygen saturation (SpO(2)) of >90%. METHODS: This prospective, observational, single-center study compared the progression and outcomes of patients who were preemptively hospitalized versus those who were hospitalized based on an SpO(2) ⩽90%. We recorded patient dem
Document: INTRODUCTION: In response to the evolution of the coronavirus disease 2019 (COVID-19) pandemic, the admission protocol for the temporary COVID-19 hospital in Mexico City has been updated to hospitalize patients preemptively with an oxygen saturation (SpO(2)) of >90%. METHODS: This prospective, observational, single-center study compared the progression and outcomes of patients who were preemptively hospitalized versus those who were hospitalized based on an SpO(2) ⩽90%. We recorded patient demographics, clinical characteristics, COVID-19 symptoms, and oxygen requirement at admission. We calculated the risk of disease progression and the benefit of preemptive hospitalization, stratified by CALL Score: age, lymphocyte count, and lactate dehydrogenase (<8 and ⩾8) at admission. RESULTS: Preemptive hospitalization significantly reduced the requirement for oxygen therapy (odds ratio 0.45, 95% confidence interval 0.31–0.66), admission to the intensive care unit (ICU) (0.37, 0.23–0.60), requirement for invasive mechanical ventilation (IMV) (0.40, 0.25–0.64), and mortality (0.22, 0.10–0.50). Stratification by CALL score at admission showed that the benefit of preemptive hospitalization remained significant for patients requiring oxygen therapy (0.51, 0.31–0.83), admission to the ICU (0.48, 0.27–0.86), and IMV (0.51, 0.28–0.92). Mortality risk remained significantly reduced (0.19, 0.07–0.48). CONCLUSION: Preemptive hospitalization reduced the rate of disease progression and may be beneficial for improving COVID-19 patient outcomes.
Search related documents:
Co phrase search for related documents- acute illness and admission referral: 1, 2
- acute illness and admission score: 1, 2, 3, 4, 5, 6
- acute illness and logistic regression model: 1, 2, 3, 4, 5
- acute illness and lymphocyte count: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15
- acute illness severity and admission score: 1
- acute illness severity and lymphocyte count: 1
- additional benefit and admission score: 1
- admission receive and logistic regression model: 1, 2, 3
- admission receive and lymphocyte count: 1, 2
- admission receive treatment and logistic regression model: 1, 2
- admission referral and logistic regression model: 1
- admission score and logistic regression model: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21
- admission score and lymphocyte count: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22
- admission treatment receive and logistic regression model: 1, 2
Co phrase search for related documents, hyperlinks ordered by date