Author: Tian Gu; Qiao Chu; Zhangsheng Yu; Botao Fa; Anqi Li; Lei Xu; Ruijun Wu; Yaping He
Title: History of Coronary Heart Disease Increases the Mortality Rate of Coronavirus Disease 2019 (COVID-19) Patients: A Nested Case-Control Study Based on Publicly Reported Confirmed Cases in Mainland China Document date: 2020_3_27
ID: nrdiqees_49
Snippet: Researchers have pointed out that severe cases may be over-represented in publicly reported data [45] . Nevertheless, we have managed to reduce the potential bias caused by severe case overrepresentation, through the appropriate matching between cases and controls in NCC design. The auto-matching procedure via statistical program also prevented the possibility of tendentiously selecting survivors with comorbidity-free history during data collecti.....
Document: Researchers have pointed out that severe cases may be over-represented in publicly reported data [45] . Nevertheless, we have managed to reduce the potential bias caused by severe case overrepresentation, through the appropriate matching between cases and controls in NCC design. The auto-matching procedure via statistical program also prevented the possibility of tendentiously selecting survivors with comorbidity-free history during data collection. In addition, NCC design is favored in our situation where the risk factor data and event of interest can be identified opportunistically from publicly reported confirmed cases [30] . Therefore, NCC was the optimal choice, given the restricted availability of public data.
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