Author: Corey M Peak; Lauren M Childs; Yonatan H Grad; Caroline O Buckee
Title: Containing Emerging Epidemics: a Quantitative Comparison of Quarantine and Symptom Monitoring Document date: 2016_8_31
ID: 2j4z5rp8_12
Snippet: To assess the impact of quarantine and symptom monitoring, we developed a general mathematical model of disease transmission and interventions targeted via contact tracing (Fig 1) . The model structure accommodates five key metrics of intervention performance in a given setting ( Table 1) . We used particle filtering to generate parameter sets consistent with seven case studies of outbreak-prone pathogens (see Methods and Table 2 ). (Figs 2A-B) ......
Document: To assess the impact of quarantine and symptom monitoring, we developed a general mathematical model of disease transmission and interventions targeted via contact tracing (Fig 1) . The model structure accommodates five key metrics of intervention performance in a given setting ( Table 1) . We used particle filtering to generate parameter sets consistent with seven case studies of outbreak-prone pathogens (see Methods and Table 2 ). (Figs 2A-B) . Under a given intervention policy, we estimate the effective reproductive number (Re) as the average number of infections generated by an infectious individual in the population. The effective reproductive number under symptom monitoring (RS), quarantine (RQ), and the absolute difference between the two ( ! − ! ) increases with R0 and differs by disease (Figs 2C-D) .
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