Selected article for: "acute infection and lung autopsy"

Author: Cîrstea, Andreea-Elena; Buzulică, Radu Lucian; Pirici, Daniel; Ceauşu, Mihail Constantin; Iman, Radu Vasile; Gheorghe, Ovidiu-Mircea; Neamţu, Simona Daniela; Stanca, Liliana; Ene, Răzvan; Kumar-Singh, Samir; Mogoantă, Laurenţiu
Title: Histopathological findings in the advanced natural evolution of the SARS-CoV-2 infection
  • Cord-id: bhuvqxnq
  • Document date: 2020_7_21
  • ID: bhuvqxnq
    Snippet: We are reporting a case of natural evolution and pathological data from a young person that was diagnosed with coronavirus disease 2019 (COVID-19). All data has been collected from the autopsy of a 30-year-old female, which was performed by the Department of Forensic Medicine from Emergency County Hospital, Drobeta Turnu Severin, Mehedinţi County, Romania. The infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was confirmed by reverse transcription polymerase chain reac
    Document: We are reporting a case of natural evolution and pathological data from a young person that was diagnosed with coronavirus disease 2019 (COVID-19). All data has been collected from the autopsy of a 30-year-old female, which was performed by the Department of Forensic Medicine from Emergency County Hospital, Drobeta Turnu Severin, Mehedinţi County, Romania. The infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was confirmed by reverse transcription polymerase chain reaction (RT–PCR) on the lung tissue which was obtained during autopsy. This case provides the opportunity to study the natural evolution of COVID-19 pneumonia in a young person with clinical signs of pneumonia but without associated comorbidities. The patient had not received any treatment. The histopathological examination of the lung revealed a process of productive proliferation, proteinaceous and fibrin-macrophagic interalveolar spaces exudate, and lesions consistent with vasculitis. In the heart, we identified a cardiac thrombus. These changes are likely to suggest an advanced natural evolution of SARS-CoV-2 virus infection.

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