Selected article for: "allele frequency and SARS cov"
Author: Daniel J Butler; Christopher Mozsary; Cem Meydan; David C Danko; Jonathan Foox; Joel Rosiene; Alon Shaiber; Ebrahim Afshinnekoo; Matthew MacKay; Fritz J Sedlazeck; Nikolay A Ivanov; Maria A Sierra; Diana Pohle; Michael Zeitz; Vijendra Ramlall; Undina Gisladottir; Craig D Westover; Krista Ryon; Benjamin Young; Chandrima Bhattacharya; Phyllis Ruggiero; Bradley W Langhorst; Nathan A Tanner; Justyn Gawrys; Dmitry Meleshko; Dong Xu; Jenny Xiang; Angelika Iftner; Daniela Bezdan; John Sipley; Lin Cong; Arryn Craney; Priya Velu; Ari Melnick; Iman A Hajirasouliha; Thomas Iftner; Mirella Salvatore; Massimo Loda; Lars F Westblade; Shawn Levy; Melissa Cushing; Nicholas P Tatonetti; Marcin Imielinski; Hanna Rennert; Christopher Mason
Title: Host, Viral, and Environmental Transcriptome Profiles of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
  • Document date: 2020_4_20
    • ID: kyoa5gsf_18
    Snippet: Among our data, we found 692 instances of variants across 89 unique variant positions across the 93 samples with sufficient quality assemblies for placement into the Nextstrain-derived maximum likelihood phylogenetic tree (see methods). Though the vast majority (>80%) of variants were present across most (>99%) SARS-CoV-2 reads aligning to a given reference position, a small subset (7%) were polymorphic with robust read coverage (>=20 reads suppo.....
    Document: Among our data, we found 692 instances of variants across 89 unique variant positions across the 93 samples with sufficient quality assemblies for placement into the Nextstrain-derived maximum likelihood phylogenetic tree (see methods). Though the vast majority (>80%) of variants were present across most (>99%) SARS-CoV-2 reads aligning to a given reference position, a small subset (7%) were polymorphic with robust read coverage (>=20 reads supporting each allele and variant allele frequency 0.1-0.9), suggesting that microdiversity may play some role in SARS-CoV-2 evolution (Figure 4) .

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