Author: Annunziata, Salvatore; Delgado Bolton, Roberto C.; Kamani, Christel-Hermann; Prior, John O.; Albano, Domenico; Bertagna, Francesco; Treglia, Giorgio
Title: Role of 2-[(18)F]FDG as a Radiopharmaceutical for PET/CT in Patients with COVID-19: A Systematic Review Cord-id: mseajzvx Document date: 2020_11_10
ID: mseajzvx
Snippet: Some recent studies evaluated the role of fluorine-18 fluorodeoxyglucose (2-[(18)F]FDG) as a radiopharmaceutical for positron emission tomography/computed tomography (PET/CT) imaging in patients with Coronavirus Disease (COVID-19). This article aims to perform a systematic review in this setting. A comprehensive computer literature search in PubMed/MEDLINE and Cochrane library databases regarding the role of 2-[(18)F]FDG PET/CT in patients with COVID-19 was carried out. This combination of key w
Document: Some recent studies evaluated the role of fluorine-18 fluorodeoxyglucose (2-[(18)F]FDG) as a radiopharmaceutical for positron emission tomography/computed tomography (PET/CT) imaging in patients with Coronavirus Disease (COVID-19). This article aims to perform a systematic review in this setting. A comprehensive computer literature search in PubMed/MEDLINE and Cochrane library databases regarding the role of 2-[(18)F]FDG PET/CT in patients with COVID-19 was carried out. This combination of key words was used: (A) “PET†OR “positron emission tomography†AND (B) “COVID†OR “SARSâ€. Only pertinent original articles were selected; case reports and very small case series were excluded. We have selected 11 original studies of 2-[(18)F]FDG PET/CT in patients with COVID-19. Evidence-based data showed first preliminary applications of this diagnostic tool in this clinical setting, with particular regard to the incidental detection of interstitial pneumonia suspected for COVID-19. To date, according to evidence-based data, 2-[(18)F]FDG PET/CT cannot substitute or integrate high-resolution CT to diagnose suspicious COVID-19 or for disease monitoring, but it can only be useful to incidentally detect suspicious COVID-19 lesions in patients performing this imaging method for standard oncological and non-oncological indications. Published data about the possible role of 2-[(18)F]FDG PET/CT in patients with COVID-19 are increasing, but larger studies are warranted.
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