Author: Austin Nguyen; Julianne K David; Sean K Maden; Mary A Wood; Benjamin R Weeder; Abhinav Nellore; Reid F Thompson
Title: Human leukocyte antigen susceptibility map for SARS-CoV-2 Document date: 2020_3_26
ID: k3y8tpps_30
Snippet: Appendix 1 contains graphical depictions of sequence alignments for 5 protein sequences (ORF1ab polyprotein, spike, envelope, membrane, and nucleocapsid) across 34 diverse coronavirus proteomes (including all 7 human coronaviruses). Appendix 2 contains a series of world maps displaying the estimated global distributions and frequencies across 145 different HLA alleles, as well as the distribution of predicted SARS-CoV-2 peptide binding and global.....
Document: Appendix 1 contains graphical depictions of sequence alignments for 5 protein sequences (ORF1ab polyprotein, spike, envelope, membrane, and nucleocapsid) across 34 diverse coronavirus proteomes (including all 7 human coronaviruses). Appendix 2 contains a series of world maps displaying the estimated global distributions and frequencies across 145 different HLA alleles, as well as the distribution of predicted SARS-CoV-2 peptide binding and global haplotype frequencies across all haplotypes containing that HLA allele. Appendix 3 contains Supplementary Tables S1-S9 S8 as follows: list of SARS-CoV-2 peptides and their predicted binding affinity across 145 HLA alleles (Supplementary Table S1 Table S8 . CC-BY-NC-ND 4.0 International license It is made available under a author/funder, who has granted medRxiv a license to display the preprint in perpetuity.
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