Author: Cruz-Lemini, Monica; Ferriols Perez, Elena; de la Cruz Conty, Maria Luisa; Caño Aguilar, Africa; Encinas Pardilla, Maria Begoña; Prats RodrÃguez, Pilar; Muner Hernando, Marta; Forcen Acebal, Laura; Pintado Recarte, Pilar; Medina Mallen, Maria del Carmen; Perez Perez, Noelia; Canet Rodriguez, Judit; Villalba Yarza, Ana; Nieto Velasco, Olga; del Barrio Fernandez, Pablo Guillermo; Orizales Lago, Carmen Maria; Marcos Puig, Beatriz; Muñoz Abellana, Begoña; Fuentes Ricoy, Laura; Rodriguez Vicente, Agueda; Janeiro Freire, Maria Jesus; Alferez Alvarez-Mallo, Macarena; Casanova Pedraz, Cristina; Alomar Mateu, Onofre; Lesmes Heredia, Cristina; Wizner de Alva, Juan Carlos; Posadas San Juan, Alma; Macia Badia, Montserrat; Alvarez Colomo, Cristina; Sanchez Muñoz, Antonio; Pratcorona Alicart, Laia; Alonso Saiz, Ruben; Lopez Rodriguez, Monica; Barbancho Lopez, Maria Carmen; Meca Casbas, Marta Ruth; Vaquerizo Ruiz, Oscar; Moran Antolin, Eva; Nuñez Valera, Maria Jose; Fernandez Fernandez, Camino; Tubau Navarra, Albert; Cano Garcia, Alejandra Maria; Soldevilla Perez, Susana; Gattaca Abasolo, Irene; Adanez Garcia, Jose; Puertas Prieto, Alberto; Ostos Serna, Rosa; Guadix Martin, Maria del Pilar; Catalina Coello, Monica; Espuelas Malon, Silvia; Sainz Bueno, Jose Antonio; Granell Escobar, Maria Reyes; Cruz Melguizo, Sara; Martinez Perez, Oscar
Title: Obstetric Outcomes of SARS-CoV-2 Infection in Asymptomatic Pregnant Women Cord-id: wit28hsc Document date: 2021_1_15
ID: wit28hsc
Snippet: Around two percent of asymptomatic women in labor test positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Spain. Families and care providers face childbirth with uncertainty. We determined if SARS-CoV-2 infection at delivery among asymptomatic mothers had different obstetric outcomes compared to negative patients. This was a multicenter prospective study based on universal antenatal screening for SARS-CoV-2 infection. A total of 42 hospitals tested women admitted for de
Document: Around two percent of asymptomatic women in labor test positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Spain. Families and care providers face childbirth with uncertainty. We determined if SARS-CoV-2 infection at delivery among asymptomatic mothers had different obstetric outcomes compared to negative patients. This was a multicenter prospective study based on universal antenatal screening for SARS-CoV-2 infection. A total of 42 hospitals tested women admitted for delivery using polymerase chain reaction, from March to May 2020. We included positive mothers and a sample of negative mothers asymptomatic throughout the antenatal period, with 6-week postpartum follow-up. Association between SARS-CoV-2 and obstetric outcomes was evaluated by multivariate logistic regression analyses. In total, 174 asymptomatic SARS-CoV-2 positive pregnancies were compared with 430 asymptomatic negative pregnancies. No differences were observed between both groups in key maternal and neonatal outcomes at delivery and follow-up, with the exception of prelabor rupture of membranes at term (adjusted odds ratio 1.88, 95% confidence interval 1.13–3.11; p = 0.015). Asymptomatic SARS-CoV-2 positive mothers have higher odds of prelabor rupture of membranes at term, without an increase in perinatal complications, compared to negative mothers. Pregnant women testing positive for SARS-CoV-2 at admission for delivery should be reassured by their healthcare workers in the absence of symptoms.
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