Author: Andrade, Viviane M.; Christensen-Quick, Aaron; Agnes, Joseph; Tur, Jared; Reed, Charles; Kalia, Richa; Marrero, Idania; Elwood, Dustin; Schultheis, Katherine; Purwar, Mansi; Reuschel, Emma; McMullan, Trevor; Pezzoli, Patrick; Kraynyak, Kim; Sylvester, Albert; Mammen, Mammen P.; Tebas, Pablo; Kim, J. Joseph; Weiner, David B.; Smith, Trevor R.F.; Ramos, Stephanie J.; Humeau, Laurent M.; Boyer, Jean D.; Broderick, Kate E.
Title: INO-4800 DNA Vaccine Induces Neutralizing Antibodies and T cell Activity Against Global SARS-CoV-2 Variants Cord-id: a451243b Document date: 2021_4_14
ID: a451243b
Snippet: Global surveillance has identified emerging SARS-CoV-2 variants of concern (VOC) associated with broadened host specificity, pathogenicity, and immune evasion to vaccine induced immunity. Here we compared humoral and cellular responses against SARS-CoV-2 VOC in subjects immunized with the DNA vaccine, INO-4800. INO-4800 vaccination induced neutralizing antibodies against all variants tested, with reduced levels detected against B.1.351. IFNγ T cell responses were fully maintained against all va
Document: Global surveillance has identified emerging SARS-CoV-2 variants of concern (VOC) associated with broadened host specificity, pathogenicity, and immune evasion to vaccine induced immunity. Here we compared humoral and cellular responses against SARS-CoV-2 VOC in subjects immunized with the DNA vaccine, INO-4800. INO-4800 vaccination induced neutralizing antibodies against all variants tested, with reduced levels detected against B.1.351. IFNγ T cell responses were fully maintained against all variants tested.
Search related documents:
Co phrase search for related documents- Try single phrases listed below for: 1
Co phrase search for related documents, hyperlinks ordered by date