Author: Austin Nguyen; Julianne K David; Sean K Maden; Mary A Wood; Benjamin R Weeder; Abhinav Nellore; Reid F Thompson
Title: Human leukocyte antigen susceptibility map for SARS-CoV-2 Document date: 2020_3_26
ID: k3y8tpps_31
Snippet: is the (which was not peer-reviewed) The copyright holder for this preprint Figure S7 : Distribution of HLA allelic presentation of 8-to 12-mers from the SARS-CoV-2 proteome using the tool MHCflurry. At right, the number of peptides (see Supplementary Table S7 ) that putatively bind to each of 66 HLA alleles is shown as a series of horizontal bars, with dark and light shading indicating the number of tightly (<50nM) and loosely (<500nM) binding p.....
Document: is the (which was not peer-reviewed) The copyright holder for this preprint Figure S7 : Distribution of HLA allelic presentation of 8-to 12-mers from the SARS-CoV-2 proteome using the tool MHCflurry. At right, the number of peptides (see Supplementary Table S7 ) that putatively bind to each of 66 HLA alleles is shown as a series of horizontal bars, with dark and light shading indicating the number of tightly (<50nM) and loosely (<500nM) binding peptides respectively, and with green, orange, and purple colors representing HLA-A, -B, and -C alleles, respectively. Alleles are sorted in descending order based on the number of peptides they bind (<500nM). The corresponding estimated allelic frequency in the global population is also shown (to left), with length of horizontal bar indicating absolute frequency in the population.
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