Selected article for: "syndrome virus and viral infection"
Author: Rad, Habib Sadeghi; Röhl, Joan; Stylianou, Nataly; Allenby, Mark C.; Bazaz, Sajad Razavi; Warkiani, Majid E.; Guimaraes, Fernando S. F.; Clifton, Vicki L.; Kulasinghe, Arutha
Title: The Effects of COVID-19 on the Placenta During Pregnancy
  • Cord-id: nay7af0r
  • Document date: 2021_9_15
    • ID: nay7af0r
    Snippet: Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global pandemic. The virus primarily affects the lungs where it induces respiratory distress syndrome ranging from mild to acute, however, there is a growing body of evidence supporting its negative effects on other system organs that also carry the ACE2 receptor, such as the placenta. The majority of newborns delivered from SARS-CoV-2 positive mothers test negative followi
    Document: Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global pandemic. The virus primarily affects the lungs where it induces respiratory distress syndrome ranging from mild to acute, however, there is a growing body of evidence supporting its negative effects on other system organs that also carry the ACE2 receptor, such as the placenta. The majority of newborns delivered from SARS-CoV-2 positive mothers test negative following delivery, suggesting that there are protective mechanisms within the placenta. There appears to be a higher incidence of pregnancy-related complications in SARS-CoV-2 positive mothers, such as miscarriage, restricted fetal growth, or still-birth. In this review, we discuss the pathobiology of COVID-19 maternal infection and the potential adverse effects associated with viral infection, and the possibility of transplacental transmission.

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