Author: François Ferron; Humberto Julio Debat; Etienne Decroly; Bruno Canard
Title: Identification of a Nidovirales Orf1a N7-guanine cap Methyltransferase signature-sequence as a genetic marker of large genome Tobaniviridae Document date: 2019_5_17
ID: lnf2mj29_20
Snippet: Then, how do Roniviridae and Tobaniviridae methylate the RNA-cap N7-guanine position? One possibility would be that these nsp16-like were bi-functional, carrying both 2'-O and N7guanine methylation activity such as evidenced in Flavivirus NS5 protein, with no obvious signature sequence of this bi-functionality. Another possibility would be that another gene author/funder. All rights reserved. No reuse allowed without permission......
Document: Then, how do Roniviridae and Tobaniviridae methylate the RNA-cap N7-guanine position? One possibility would be that these nsp16-like were bi-functional, carrying both 2'-O and N7guanine methylation activity such as evidenced in Flavivirus NS5 protein, with no obvious signature sequence of this bi-functionality. Another possibility would be that another gene author/funder. All rights reserved. No reuse allowed without permission.
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