Selected article for: "acute respiratory syndrome and renal failure"
Author: Bo Diao; Chenhui Wang; Rongshuai Wang; Zeqing Feng; Yingjun Tan; Huiming Wang; Changsong Wang; Liang Liu; Ying Liu; Yueping Liu; Gang Wang; Zilin Yuan; Liang Ren; Yuzhang Wu; Yongwen Chen
Title: Human Kidney is a Target for Novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection
  • Document date: 2020_3_6
    • ID: bpnqz1cn_1
    Snippet: In December 2019, a cluster of pneumonia cases caused by a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were reported in Wuhan, Hubei Province, China. 1 Some studies have suggested that SARS-CoV-2, SARS-CoV (Severe acute respiratory syndrome-Coronavirus) and MERS-CoV (Middle East Respiratory Syndrome-Coronavirus) share a common ancestor resembling the bat coronavirus HKU9-1. 8, 9 Recently, Shi et al., reported that SARS-CoV-.....
    Document: In December 2019, a cluster of pneumonia cases caused by a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were reported in Wuhan, Hubei Province, China. 1 Some studies have suggested that SARS-CoV-2, SARS-CoV (Severe acute respiratory syndrome-Coronavirus) and MERS-CoV (Middle East Respiratory Syndrome-Coronavirus) share a common ancestor resembling the bat coronavirus HKU9-1. 8, 9 Recently, Shi et al., reported that SARS-CoV-2 interacts with human ACE2 (angiotensin converting enzyme-II) molecules via its Spike protein. 10 In addition to respiratory organs, the expression of ACE2 protein has also been observed in human kidneys, 11, 12 and Cheng et al., reported that some COVID-19 patients had an elevated level of proteinuria. 13 However, no evidence directly demonstrates that SARS-CoV-2 can infect the kidney to cause acute renal failure.

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