Selected article for: "cell analysis and RNA seq"
Author: Wen Wen; Wenru Su; Hao Tang; Wenqing Le; Xiaopeng Zhang; Yingfeng Zheng; XiuXing Liu; Lihui Xie; Jianmin Li; Jinguo Ye; Xiuliang Cui; Yushan Miao; Depeng Wang; Jiantao Dong; Chuan-Le Xiao; Wei Chen; Hongyang Wang
Title: Immune Cell Profiling of COVID-19 Patients in the Recovery Stage by Single-Cell Sequencing
  • Document date: 2020_3_27
    • ID: 8aezcyf9_7
    Snippet: To map the immune microenvironment of COVID-19 patients, we identified mirroring changes in the blood and pinpointed cell-specific alterations associated with disease severity and recovery; we then integrated single-cell RNA sequencing (scRNA-seq), single-cell paired BCR, and single-cell paired TCR analysis from a total of 10 COVID-19 patients in the early recovery stage (ERS) or late recovery stage (LRS) (70,858 PBMCs). We also collected scRNA-s.....
    Document: To map the immune microenvironment of COVID-19 patients, we identified mirroring changes in the blood and pinpointed cell-specific alterations associated with disease severity and recovery; we then integrated single-cell RNA sequencing (scRNA-seq), single-cell paired BCR, and single-cell paired TCR analysis from a total of 10 COVID-19 patients in the early recovery stage (ERS) or late recovery stage (LRS) (70,858 PBMCs). We also collected scRNA-seq data (57,238 cells) from five healthy donors as controls ( Fig. 1A and Fig. S1 ). This dataset passed stringent high-quality filtering.

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