Selected article for: "cell surface and host cell"
Author: Huan Ma; Weihong Zeng; Hongliang He; Dan Zhao; Yunru Yang; Dehua Jiang; Peigen Zhou; Yingjie Qi; Weihuang He; Changcheng Zhao; Ruting Yi; Xiaofang Wang; Bo Wang; Yuanhong Xu; Yun Yang; Arnaud John Kombe Kombe; Chengchao Ding; Jiajia Xie; Yong Gao; Linzhao Cheng; Yajuan Li; Xiaoling Ma; Tengchuan Jin
Title: COVID-19 diagnosis and study of serum SARS-CoV-2 specific IgA, IgM and IgG by a quantitative and sensitive immunoassay
  • Document date: 2020_4_22
    • ID: 4jeaqqn9_44
    Snippet: Our serological kits have overall good performance 326 Our kits have much higher accuracy than RT-qPCR (sensitivity less than 70%) for detecting viral 327 RNA 9-13 , and published immune-assays such as " flow immunoassay" and ELISA in earlier studies 10-12, 328 17-21, 23, 24 . When we combined RBD-specific IgA and IgG kits together, the sensitivity, specificity and 329 overall agreement elevate to 99· 1%, 100%, and 99· 7%, respectively (table 1.....
    Document: Our serological kits have overall good performance 326 Our kits have much higher accuracy than RT-qPCR (sensitivity less than 70%) for detecting viral 327 RNA 9-13 , and published immune-assays such as " flow immunoassay" and ELISA in earlier studies 10-12, 328 17-21, 23, 24 . When we combined RBD-specific IgA and IgG kits together, the sensitivity, specificity and 329 overall agreement elevate to 99· 1%, 100%, and 99· 7%, respectively (table 1). In addition, this RBD-330 based detection kit may also help to screen and detect neutralization antibodies targeting SARS-CoV-2 331 RBD, because this peptide domain is exposed on viral surface and functions as a ligand binding to the 332 host cell surface receptor ACE2.

    Search related documents:
    Co phrase search for related documents
    • cell surface and early study: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
    • cell surface and flow immunoassay: 1
    • cell surface and function viral surface: 1
    • cell surface and high accuracy: 1, 2
    • cell surface and neutralization antibody: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13
    • cell surface and peptide domain: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14
    • cell surface and viral surface: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • cell surface receptor and neutralization antibody: 1, 2, 3, 4
    • cell surface receptor and peptide domain: 1, 2
    • cell surface receptor and viral surface: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • detection kit and ELISA flow immunoassay: 1, 2
    • detection kit and flow immunoassay: 1, 2, 3, 4, 5, 6
    • detection kit and good performance: 1, 2, 3
    • detection kit and high accuracy: 1, 2
    • detection kit and ligand bind: 1
    • detection kit and neutralization antibody: 1, 2, 3, 4, 5, 6, 7
    • detection kit and overall agreement: 1, 2
    • detection kit and serological kit: 1, 2
    • detection kit and viral surface: 1, 2