Selected article for: "Î expression and IFN Î expression"

Author: Jun Wu; Dingyun Song; Zhongwen Li; Baojie Guo; Yani Xiao; Wenjing Liu; Lingmin Liang; Chunjing Feng; Tingting Gao; Zai Wang; Jianyan Wen; Shengnan Yang; Peipei Liu; Lei Wang; Yukai Wang; Liang Peng; Guihai Feng; Shiqiang Huang; Glyn Nigel Stacey; Wei Li; Yan Huo; Ronghua Jin; Qi Zhou; Liu Wang; Baoyang Hu; Huaping Dai; Jie Hao
Title: Immunity-and-Matrix-Regulatory Cells Derived from Human Embryonic Stem Cells Safely and Effectively Treat Mouse Lung Injury and Fibrosis
  • Document date: 2020_4_16
  • ID: 8dpla6jt_49
    Snippet: To test the immunomodulatory capacity of IMRCs, we exposed them to the pro-inflammatory cytokine 410 IFN-γ. We found that after stimulation with IFN-γ, both primary UCMSCs and IMRCs displayed similar 411 characteristic morphological changes (Fig. 3A) . IFN-γ stimulation also potently upregulated IDO1 412 expression in both primary UCMSCs and IMRCs, but much more significantly so in IMRCs (Fig. 3B) . 413.....
    Document: To test the immunomodulatory capacity of IMRCs, we exposed them to the pro-inflammatory cytokine 410 IFN-γ. We found that after stimulation with IFN-γ, both primary UCMSCs and IMRCs displayed similar 411 characteristic morphological changes (Fig. 3A) . IFN-γ stimulation also potently upregulated IDO1 412 expression in both primary UCMSCs and IMRCs, but much more significantly so in IMRCs (Fig. 3B) . 413

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