Author: Yue-qiang Fu; Yue-lin Sun; Si-wei Lu; Yang Yang; Yi Wang; Feng Xu
Title: Impact of blood analysis and immune function on the prognosis of patients with COVID-19 Document date: 2020_4_22
ID: a822exap_52
Snippet: At present, there is no study about humoral immunity function of patients with COVID-19. We found that the difference of IgG, IgM, IgA, C3, C4 and the percentage of IgE > 100 IU/ml was not significant between the survivors and non-survivors. The baseline platelet level in patients who died was lower than that of the survivors. Reference to other virus researches, this may be due to platelet destruction caused by the virus, or inhibition of the pr.....
Document: At present, there is no study about humoral immunity function of patients with COVID-19. We found that the difference of IgG, IgM, IgA, C3, C4 and the percentage of IgE > 100 IU/ml was not significant between the survivors and non-survivors. The baseline platelet level in patients who died was lower than that of the survivors. Reference to other virus researches, this may be due to platelet destruction caused by the virus, or inhibition of the production of platelets in bone marrow via viral infection [20], or platelet consumption caused by the formation of thrombus at the injured site of lung [21, 22] . The hemoglobin level in the dead patients is higher than that in the surviving patients, which may be due to the severe lung injury in the dead patients and the irritant increase of hemoglobin caused by hypoxemia.
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