Selected article for: "improved transport and molecular diversity"
Author: Rashmi Mohanty; Xinquan Liu; Jae You Kim; Xiujuan Peng; Sahil Bhandari; Jasmim Leal; Dhivya Arasappan; Dennis C. Wylie; Tony Dong; Debadyuti Ghosh
Title: Identification of peptide coatings that enhance diffusive transport of nanoparticles through the tumor microenvironment
  • Document date: 2019_6_4
    • ID: e2uzk4u1_16
    Snippet: In this work we use phage display technology as a combinatorial approach to generate and identify peptides as surface coatings to achieve improved diffusive transport through the tumor microenvironment. Phage, or bacterial viruses, can be genetically engineered to display peptides on their protein coat and can be pooled together to generate a collection of peptide-presenting phage libraries with excellent molecular diversity (i.e. 10 5 -10 9 diff.....
    Document: In this work we use phage display technology as a combinatorial approach to generate and identify peptides as surface coatings to achieve improved diffusive transport through the tumor microenvironment. Phage, or bacterial viruses, can be genetically engineered to display peptides on their protein coat and can be pooled together to generate a collection of peptide-presenting phage libraries with excellent molecular diversity (i.e. 10 5 -10 9 different peptide sequences) 64 .

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