Selected article for: "cell surface and Leiden clustering"
Author: Hema Kothari; Corey M. Williams; Chantel McSkimming; Mythili Vigneshwar; Eli R. Zunder; Coleen A. McNamara
Title: Identification of Human Immune Cell Subtypes Most Vulnerable to IL-1ß-induced Inflammatory Signaling Using Mass Cytometry
  • Document date: 2020_4_19
    • ID: 5rhn7gom_42
    Snippet: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.19.047274 doi: bioRxiv preprint UMAP followed by Leiden clustering was performed on gated CD3 -CD19 -CD56 -HLA-DR + cells using both vehicle and IL-1β-stimulated cells using cell surface markers as shown in c. a, 12 cell clusters that included monocyte and DC cells were identified as shown superimposed on the UMAP. b, Frequency of 12 sub.....
    Document: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.19.047274 doi: bioRxiv preprint UMAP followed by Leiden clustering was performed on gated CD3 -CD19 -CD56 -HLA-DR + cells using both vehicle and IL-1β-stimulated cells using cell surface markers as shown in c. a, 12 cell clusters that included monocyte and DC cells were identified as shown superimposed on the UMAP. b, Frequency of 12 subsets and inter-individual variations. c, Heatmap showing median expression of surface markers across all 12 cell clusters. Frequency of d, p-NF-kB + cells and e, p-p38+ cells within each cluster in the vehicle-treated and IL-1β-stimulated samples. Significant differences represent the comparisons between vehicle and IL-1β-stimulated samples. Data shown is mean ± SEM. Paired t-test. N=3; * p-value ≤ 0.05. author/funder. All rights reserved. No reuse allowed without permission.

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