Author: Bicheng Zhang; Xiaoyang Zhou; Chengliang Zhu; Fan Feng; Yanru Qiu; Jia Feng; Qingzhu Jia; Qibin Song; Bo Zhu; Jun Wang
Title: Immune phenotyping based on neutrophil-to-lymphocyte ratio and IgG predicts disease severity and outcome for patients with COVID-19 Document date: 2020_3_16
ID: 68193u0a_19
Snippet: As shown in table 1, severe patients had higher proinflammatory cytokines levels including IL-2, IL-6 and IL-10 than nonsevere patients, especially in the NLR hi IgG hi or NLR hi IgG lo phenotype (p<0.05). Furthermore, severe patients with the NLR hi IgG hi or NLR hi IgG lo phenotype had higher proinflammatory cytokines levels including IL-2, IL-6 and IL-10, and decreased CD4+ T cell count, compared to those with the NLR lo IgG lo phenotype (p<0......
Document: As shown in table 1, severe patients had higher proinflammatory cytokines levels including IL-2, IL-6 and IL-10 than nonsevere patients, especially in the NLR hi IgG hi or NLR hi IgG lo phenotype (p<0.05). Furthermore, severe patients with the NLR hi IgG hi or NLR hi IgG lo phenotype had higher proinflammatory cytokines levels including IL-2, IL-6 and IL-10, and decreased CD4+ T cell count, compared to those with the NLR lo IgG lo phenotype (p<0.05). In particular, only IgG and IgM were higher in severe patients with the NLR lo IgG hi phenotype than those in the NLR lo IgG lo phenotype (p<0.05).
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