Author: Chu, Daniel K.W.; Hui, Kenrie P.Y.; Gu, Haogao; Ko, Ronald L.W.; Krishnan, Pavithra; Ng, Daisy Y.M.; Liu, Gigi Y.Z.; Wan, Carrie K.C.; Cheung, Man-Chun; Ng, Ka-Chun; Nicholls, John M.; Tsang, Dominic N.C.; Peiris, Malik; Chan, Michael C.W.; Poon, Leo L.M.
Title: Introduction of ORF3a-Q57H SARS-CoV-2 Variant Causing Fourth Epidemic Wave of COVID-19, Hong Kong, China Cord-id: cc1qq0ir Document date: 2021_5_25
ID: cc1qq0ir
Snippet: We describe an introduction of clade GH severe acute respiratory syndrome coronavirus 2 causing a fourth wave of coronavirus disease in Hong Kong. The virus has an ORF3a-Q57H mutation, causing truncation of ORF3b. This virus evades induction of cytokine, chemokine, and interferon-stimulated gene expression in primary human respiratory cells.
Document: We describe an introduction of clade GH severe acute respiratory syndrome coronavirus 2 causing a fourth wave of coronavirus disease in Hong Kong. The virus has an ORF3a-Q57H mutation, causing truncation of ORF3b. This virus evades induction of cytokine, chemokine, and interferon-stimulated gene expression in primary human respiratory cells.
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