Author: Priya Swetha, P. D.; Sonia, J.; Sapna, K.; Prasad, K. Sudhakara
Title: Towards CRISPR powered Electrochemical sensing for Smart diagnostics Cord-id: p19bx8os Document date: 2021_1_1
ID: p19bx8os
Snippet: Even though global health has been steadily improved, the global disease burden associated with communicable and non-communicable disease extensively increased healthcare expenditure. Present COVID-19 pandemic scenario has again ascertained the importance of clinical diagnostics as basis to make life-saving decisions. In this context, there is a need for developing next-generation integrated smart real-time responsive biosensors with high selectivity and sensitivity. The emergence of CRISPR/Cas
Document: Even though global health has been steadily improved, the global disease burden associated with communicable and non-communicable disease extensively increased healthcare expenditure. Present COVID-19 pandemic scenario has again ascertained the importance of clinical diagnostics as basis to make life-saving decisions. In this context, there is a need for developing next-generation integrated smart real-time responsive biosensors with high selectivity and sensitivity. The emergence of CRISPR/Cas biosensing systems has shown remarkable potential for developing next-generation biosensors. CRISPR/Cas integrated electrochemical biosensors (E-CRISPR) stands out with excellent properties. In this opinionated review, we illustrate the rapidly evolving applications for E-CRISPR integrated detection systems towards biosensing, and future scope associated with E-CRISPR based diagnostics.
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