Author: Jun Wu; Dingyun Song; Zhongwen Li; Baojie Guo; Yani Xiao; Wenjing Liu; Lingmin Liang; Chunjing Feng; Tingting Gao; Zai Wang; Jianyan Wen; Shengnan Yang; Peipei Liu; Lei Wang; Yukai Wang; Liang Peng; Guihai Feng; Shiqiang Huang; Glyn Nigel Stacey; Wei Li; Yan Huo; Ronghua Jin; Qi Zhou; Liu Wang; Baoyang Hu; Huaping Dai; Jie Hao
Title: Immunity-and-Matrix-Regulatory Cells Derived from Human Embryonic Stem Cells Safely and Effectively Treat Mouse Lung Injury and Fibrosis Document date: 2020_4_16
ID: 8dpla6jt_69
Snippet: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.15.042119 doi: bioRxiv preprint 19 tumorigenic potential as determined by this assay. Somatic mutation analysis by whole genome 484 sequencing also showed zero mutations in all coding and noncoding exon regions of the IMRCs genome 485 (Fig. 5F ). Tumor formation assays also confirmed that IMRCs could not form any tumors in 486 immunodefic.....
Document: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.15.042119 doi: bioRxiv preprint 19 tumorigenic potential as determined by this assay. Somatic mutation analysis by whole genome 484 sequencing also showed zero mutations in all coding and noncoding exon regions of the IMRCs genome 485 (Fig. 5F ). Tumor formation assays also confirmed that IMRCs could not form any tumors in 486 immunodeficient mice after injection in vivo (Supplementary Table S1 ). 487
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