Selected article for: "health problem and severe health problem"

Author: Huang, Boxuan; Ling, Rongsong; Cheng, Yifan; Wen, Jieqi; Dai, Yarong; Huang, Wenjie; Zhang, Siyan; Lu, Xifeng; Luo, Yifeng; Jiang, Yi-Zhou
Title: Characteristics and Therapeutic Options of the Coronavirus Disease 2019
  • Cord-id: b69zgnku
  • Document date: 2020_6_24
  • ID: b69zgnku
    Snippet: Abstract The Coronavirus Disease 2019 (COVID-19) is a new type of pneumonia caused by SARS-CoV-2 infection. COVID-19 is affecting millions of patients and the infected number keeps increasing. SARS-CoV-2 is highly infectious, has a long incubation period, and causes a relatively high death rate, resulting in severe health problem all over the world. Currently there is no effective proven drugs for the treatment of COVID-19, therefore, development of effective therapeutic drugs to suppress SARS-C
    Document: Abstract The Coronavirus Disease 2019 (COVID-19) is a new type of pneumonia caused by SARS-CoV-2 infection. COVID-19 is affecting millions of patients and the infected number keeps increasing. SARS-CoV-2 is highly infectious, has a long incubation period, and causes a relatively high death rate, resulting in severe health problem all over the world. Currently there is no effective proven drugs for the treatment of COVID-19, therefore, development of effective therapeutic drugs to suppress SARS-CoV-2 infection is urgently needed. In this review, we first summarize the structure and genome features of SARS-CoV-2, and introduce its infection and replication process. Then we review the clinical symptoms, diagnosis and treatment options of COVID-19 patients. We further discuss the potential molecular targets and drug development strategies for treatment of the emerging COVID-19. Finally, we summarize clinical trials of some potential therapeutic drugs and the results of vaccine development. This review provides some insights for the treatment of COVID-19.

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