Layered Double Hydroxide Nanomaterials: Biomedical Applications, Current Status and Challenges

Sharma, Ritika Bhawna Kumar Sanjeev Singh Poonam Gupta Akanksha Kumar Vinod

Layered double hydroxide nanomaterials (LDH NMs) have been dragging the researchers’ attention toward biomedical applications owing to their physiochemical properties, biocompatibility, environmental sensitivity and good cellular uptake mechanisms. Various synthetic methods have been presented in brief. This paper draws attention toward the modification and functionalization of LDH nanostructures for biomedical applications in targeted and controlled drug release, anticancer, bioimaging, bone therapy and regeneration, gene delivery, ophthalmic and antitumor activities. Further, it explains the properties of conjugated LDH NMs which put forward their possibilities to be used in synthesizing the most demanding vaccine for COVID-19 pandemic. Current scenario, challenges and future perspective of LDH NMs have also been discussed. [ABSTRACT FROM AUTHOR] Copyright of Nano Life is the property of World Scientific Publishing Company and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)