Author: Martin Bartas; Václav Brázda; Natália Bohálová; Alessio Cantara; Adriana Volná; Tereza Stachurová; Katerina Malachová; Eva B. Jagelská; Otília Porubiaková; Jirí Cerven; Petr Pecinka
Title: In-depth Bioinformatic Analyses of Human SARS-CoV-2, SARS-CoV, MERS-CoV, and Other Nidovirales Suggest Important Roles of Noncanonical Nucleic Acid Structures in Their Lifecycles Document date: 2020_4_11
ID: d3q0xel1_52
Snippet: The organelles can undergo transition from liquid-like droplets to amyloid fibrils, and mutations in socalled low complexity domains of these proteins lead to formation of amyloid aggregations that are found in many neurodegenerative diseases (Gui et al., 2019) . HNRNPA1 is involved in many different cellular processes and has been targeted in various diseases. One such example is the varicella zoster virus that causes chicken pox. Moreover, this.....
Document: The organelles can undergo transition from liquid-like droplets to amyloid fibrils, and mutations in socalled low complexity domains of these proteins lead to formation of amyloid aggregations that are found in many neurodegenerative diseases (Gui et al., 2019) . HNRNPA1 is involved in many different cellular processes and has been targeted in various diseases. One such example is the varicella zoster virus that causes chicken pox. Moreover, this response to varicella zoster virus has been connected with autoimmune disease that complicates multiple sclerosis (Kattimani and Veerappa, 2018) .
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