Author: Qingxin Zhang; Qingshun Zhao
Title: Inactivating porcine coronavirus before nuclei acid isolation with the temperature higher than 56 °C damages its genome integrity seriously Document date: 2020_2_22
ID: 0vjs2w3l_1
Snippet: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) or 2019-Novel Coronavirus (2019-nCoV) is the pathogen of Corona Virus Disease 2019 [1] . Nucleic acid detection of 2019-nCoV is one of the key indicators for clinical diagnosis. However, the false negative rate of 2019-nCoV nucleic acid in clinical practice is very high, and the positive rate is only 30-50% [2] . False negative detection means missed detection, which will lead to not on.....
Document: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) or 2019-Novel Coronavirus (2019-nCoV) is the pathogen of Corona Virus Disease 2019 [1] . Nucleic acid detection of 2019-nCoV is one of the key indicators for clinical diagnosis. However, the false negative rate of 2019-nCoV nucleic acid in clinical practice is very high, and the positive rate is only 30-50% [2] . False negative detection means missed detection, which will lead to not only the delayed diagnosis of suspected patients, but also the 2019-nCoV carriers becoming the potential sources of virus infection. Therefore, it is very urgent to improve the detection rate of 2019-nCoV nucleic acid clinically.
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