Author: Bailey, Dana; Konforte, Danijela; Barakauskas, Vilte E.; Yip, Paul M.; Kulasingam, Vathany; Abou El Hassan, Mohamed; Beach, Lori A.; Blasutig, Ivan M.; Catomeris, Peter; Dooley, Kent C.; Gong, Yanping; Kavsak, Peter; Randell, Edward W; Robinson, Jason L; Shaw, Julie; Taher, Jennifer; White-Al Habeeb, Nicole
Title: Canadian Society of Clinical Chemists (CSCC) Interim Consensus Guidance for Testing and Reporting of SARS-CoV-2 Serology Cord-id: nw6xk4ai Document date: 2020_10_6
ID: nw6xk4ai
Snippet: Clinical laboratories across the world are working to validate and perform testing for SARS-CoV-2 antibodies. Herein, we present interim consensus guidance for Canadian clinical laboratories testing and reporting SARS-CoV-2 serology, with emphasis on the capabilities and limitations of these tests and recommendations for interpretative comments in an effort to achieve harmonized laboratory practices. The consensus document provides a broad overview of topics including sample type and contaminati
Document: Clinical laboratories across the world are working to validate and perform testing for SARS-CoV-2 antibodies. Herein, we present interim consensus guidance for Canadian clinical laboratories testing and reporting SARS-CoV-2 serology, with emphasis on the capabilities and limitations of these tests and recommendations for interpretative comments in an effort to achieve harmonized laboratory practices. The consensus document provides a broad overview of topics including sample type and contamination risk; kinetics of antibody response to COVID-19 and the impact on serology testing; clinical utility of SARS-CoV-2 serology testing; clinical performance of commercial laboratory-based assays commonly deployed in North America; recommendations for interim reporting; utility of SARS-CoV-2 antibody testing for pediatric patients; and utility of point-of-care testing. The information is based on the current literature and is subject to change as additional information becomes available.
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