Selected article for: "lung function and pulmonary lung function"
Author: Spagnolello, Ornella; Pinacchio, Claudia; Santinelli, Letizia; Vassalini, Paolo; Innocenti, Giuseppe Pietro; De Girolamo, Gabriella; Fabris, Silvia; Giovanetti, Marta; Angeletti, Silvia; Russo, Alessandro; Mastroianni, Claudio M.; Ciccozzi, Massimo; Ceccarelli, Giancarlo; d'Ettorre, Gabriella
Title: Targeting Microbiome: An Alternative Strategy for Fighting SARS-CoV-2 Infection
  • Cord-id: bjv21q29
  • Document date: 2021_3_23
    • ID: bjv21q29
    Snippet: Respiratory and gastrointestinal symptoms are the predominant clinical manifestations of the coronavirus disease 2019 (COVID-19). Infecting intestinal epithelial cells, the severe acute respiratory syndrome coronavirus-2 may impact on host's microbiota and gut inflammation. It is well established that an imbalanced intestinal microbiome can affect pulmonary function, modulating the host immune response (“gut-lung axis”). While effective vaccines and targeted drugs are being tested, alternati
    Document: Respiratory and gastrointestinal symptoms are the predominant clinical manifestations of the coronavirus disease 2019 (COVID-19). Infecting intestinal epithelial cells, the severe acute respiratory syndrome coronavirus-2 may impact on host's microbiota and gut inflammation. It is well established that an imbalanced intestinal microbiome can affect pulmonary function, modulating the host immune response (“gut-lung axis”). While effective vaccines and targeted drugs are being tested, alternative pathophysiology-based options to prevent and treat COVID-19 infection must be considered on top of the limited evidence-based therapy currently available. Addressing intestinal dysbiosis with a probiotic supplement may, therefore, be a sensible option to be evaluated, in addition to current best available medical treatments. Herein, we summed up pathophysiologic assumptions and current evidence regarding bacteriotherapy administration in preventing and treating COVID-19 pneumonia.

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