Introduction to the Concepts of Agr-Informatics

Singh, Sidharth; Haque, M. Aafikul; Silakari, Om

Bioinformatics is an emerging field which involves various other interdisciplinary science such as computer science, mathematical science, molecular biology, and statistical sciences. Bioinformatics applies computational solutions to complex biological problems like protein modeling, predicting the binding profile of a drug molecule for its target, predicting how a drug molecule will behave in vivo. In this chapter we have provided a brief introduction to bioinformatics covering some basic biological terminology and different types of databases. We have also discussed various sequence alignment procedures in detail which are used to perform evolutionary analysis for different species. Sequence alignment helps us to identify the evolutionary distance among various species. Sequence alignment is of two types: pairwise and multiple. In pairwise sequence alignment only two sequences are compared in contrast to multiple sequence alignment where more than two sequences can be analyzed. We have also discussed the methods for phylogenetic tree construction using different methods.