A New Hematological Prognostic Index For Covid-19 Severity

Hammadi, Abdulmajeed A.; Jubouri, Adnan M. Al; Ahmed, Ghassan; Hayyawi, Ali H.; Kareem, Khalil; Gorial, Faiq I.; Salman, Muhammed Waheeb; Ghanim, Mohammed; Jameel, Basil F.; Jawad, Ali M.; Abbas, Hassan M.; Al-Gharawi, Ali A.; Al-shareef, Jawad I; Ali, Chasib L.; Nasser, Kawthar F.; Abdulrazaq, Mohammad Y.

Backgroundsevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or Covid-19 is a nationwide public health emergency with significant impact on human life. ObjectiveTo develop a new simple hematological prognostic index for Covid-19 severity state. Patients and methodsThis observational cross sectional study was conducted on 250 patients with Covid-19 disease. Age, gender, and severity of Covid -19 were recorded. Complete blood count and lactate dehydrogenase were measured. New index: COVID-19 severity-Iraqi-index = CSI index to predict COVID-19 severity. CSI index is monocyte/lymphocyte absolute counts multiplied by LDH (lactate dehydrogenase)/upper normal reference laboratory range of LDH value. ResultsMean age of patients was 50.4 + 15.1 years. Majority of patients were Males 148 (59.2%)..Most of patients were in stage 2 and 3 (> 94%). There was a significant difference between means of White Blood Cells, lymphocytes and Monocytes among the different stages of the disease (P = 0.0001, 0.036, 0.012). There was a significant moderate correlation between the prognostic index and the stage of the disease (r=0.41, p=0.0001). ConclusionsCSI index is a new simple predictor of clinical outcome in patients with covid-19 during early stage of the disease.