Author: Ramya Rangan; Andrew M. Watkins; Wipapat Kladwang; Rhiju Das
Title: De novo 3D models of SARS-CoV-2 RNA elements and small-molecule-binding RNAs to guide drug discovery Document date: 2020_4_15
ID: 7gm92gau_15_1
Snippet: rithms. As a preview of such modeling, we used the crystal structure of the SARS stem-loop II-like motif (s2m) to build over 200,000 homology models for the SARS-CoV-2 s2m with FARFAR2 (Fig. 4B , see Methods). 5, 26 With near-identical sequences, the SARS s2m template crystal structure is already a near-complete model for the SARS-Cov-2 domain, such that the FARFAR2 homology models for this region are highly converged (0.21 Ã…)......
Document: rithms. As a preview of such modeling, we used the crystal structure of the SARS stem-loop II-like motif (s2m) to build over 200,000 homology models for the SARS-CoV-2 s2m with FARFAR2 (Fig. 4B , see Methods). 5, 26 With near-identical sequences, the SARS s2m template crystal structure is already a near-complete model for the SARS-Cov-2 domain, such that the FARFAR2 homology models for this region are highly converged (0.21 Ã…).
Search related documents:
Co phrase search for related documents- crystal structure and near identical sequence: 1, 2
- crystal structure and SARS domain: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52
- crystal structure and stem loop: 1, 2, 3, 4, 5, 6, 7, 8, 9
- crystal structure and template crystal structure: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
- homology model and region homology model: 1, 2
- homology model and SARS domain: 1, 2
- homology model and stem loop: 1, 2
- homology model and template crystal structure: 1, 2
- SARS domain and stem loop: 1, 2, 3, 4, 5, 6
- SARS domain and template crystal structure: 1
Co phrase search for related documents, hyperlinks ordered by date