Author: Duan, Zhen; Liu, Mandie; Yuan, Lin; Du, Xizi; Wu, Mengping; Yang, Yu; Wang, Leyuan; Zhou, Kai; Yang, Ming; Zou, Yizhou; Xiang, Yang; Qu, Xiangping; Liu, Huijun; Qin, Xiaoqun; Liu, Chi
Title: Innate lymphoid cells are doubleâ€edged swords under the mucosal barrier Cord-id: o1bdqyeh Document date: 2021_8_10
ID: o1bdqyeh
Snippet: As the direct contacting site for pathogens and allergens, the mucosal barrier plays a vital role in the lungs and intestines. Innate lymphoid cells (ILCs) are particularly resident in the mucosal barrier and participate in several pathophysiological processes, such as maintaining or disrupting barrier integrity, preventing various pathogenic invasions. In the pulmonary mucosae, ILCs sometimes aggravate inflammation and mucus hypersecretion but restore airway epithelial integrity and maintain lu
Document: As the direct contacting site for pathogens and allergens, the mucosal barrier plays a vital role in the lungs and intestines. Innate lymphoid cells (ILCs) are particularly resident in the mucosal barrier and participate in several pathophysiological processes, such as maintaining or disrupting barrier integrity, preventing various pathogenic invasions. In the pulmonary mucosae, ILCs sometimes aggravate inflammation and mucus hypersecretion but restore airway epithelial integrity and maintain lung tissue homeostasis at other times. In the intestinal mucosae, ILCs can increase epithelial permeability, leading to severe intestinal inflammation on the one hand, and assist mucosal barrier in resisting bacterial invasion on the other hand. In this review, we will illustrate the positive and negative roles of ILCs in mucosal barrier immunity.
Search related documents:
Co phrase search for related documents- acute infection and local inflammation: 1, 2, 3, 4, 5, 6, 7, 8
- acute infection and local microenvironment: 1
- acute infection and long term damage: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13
- acute infection and lung disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73
- acute infection and lung disease outcome: 1
- acute infection and lung homeostasis: 1, 2, 3, 4
- acute infection and lung immunity: 1, 2, 3, 4, 5, 6, 7, 8, 9
- liver lung and local inflammation: 1
- liver lung and lung disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47
- liver lung and lung homeostasis: 1, 2
- liver lung and lung mucosa: 1, 2, 3
- local inflammation and lung disease: 1, 2, 3, 4
- local inflammation and lung immunity: 1, 2
- local microenvironment and lung disease: 1
- local microenvironment and lung homeostasis: 1
- local microenvironment and lung immunity: 1, 2
- long term damage and lung disease: 1, 2
Co phrase search for related documents, hyperlinks ordered by date