Selected article for: "important factor and SARS cov"
Author: Suhren, Jan-Theile; Meinardus, Andre; Hussein, Kais; Schaumann, Nora
Title: Meta-analysis on COVID-19-pregnancy-related placental pathologies shows no specific pattern
  • Cord-id: c3mwsazo
  • Document date: 2021_10_19
    • ID: c3mwsazo
    Snippet: Coronavirus disease 2019 (COVID-19) pneumonia rarely occur in pregnant women. Case reports indicate that fibrin and lymphohistiocytic lesions in placentas may be typical. However, a meta-analysis to clarify whether there is a COVID-19-associated pattern of placental lesions has not yet been conducted. Systematic literature search with meta-analysis of publications on 10 or more cases of pregnancy with SARS-CoV-2 infection and placenta examination (30 publications from 2019-2021; 1452 placenta ca
    Document: Coronavirus disease 2019 (COVID-19) pneumonia rarely occur in pregnant women. Case reports indicate that fibrin and lymphohistiocytic lesions in placentas may be typical. However, a meta-analysis to clarify whether there is a COVID-19-associated pattern of placental lesions has not yet been conducted. Systematic literature search with meta-analysis of publications on 10 or more cases of pregnancy with SARS-CoV-2 infection and placenta examination (30 publications from 2019-2021; 1452 placenta cases). The meta-analysis did not reveal any COVID-19-specific placenta changes. The incidence of both vascular and inflammatory lesions was mainly comparable to that of non-COVID-19 pregnancies. Transplacental viral transmission is very rare and there are no typical placental changes. The most important prognostic factor seems to be maternal-fetal hypoxia in the context of pneumonia.

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