Author: Chang, Jaimie; Bulwa, Zachary; Breit, Hannah; Cherian, Laurel J.; Conners, James J.; Song, Sarah Y.; Dafer, Rima M.
Title: Acute Large Vessel Ischemic Stroke in Patients with COVID-19 Related Multisystem Inflammatory Syndrome Cord-id: o8quzzyg Document date: 2021_9_25
ID: o8quzzyg
Snippet: BACKGROUND: Acute ischemic stroke (AIS) is rare in children and diagnosis is often delayed. Neurological involvement may occur in multisystem inflammatory syndrome in children (MIS-C), but very few cases of AIS in patients with MIS-C have been reported. CASE DESCRIPTIONS: We report two cases of AIS presenting with large vessel occlusive (LVO) disease in previously healthy adolescents recently exposed to SARS-CoV-2 infection. Both patients were subsequently diagnosed with and treated for MIS-C. H
Document: BACKGROUND: Acute ischemic stroke (AIS) is rare in children and diagnosis is often delayed. Neurological involvement may occur in multisystem inflammatory syndrome in children (MIS-C), but very few cases of AIS in patients with MIS-C have been reported. CASE DESCRIPTIONS: We report two cases of AIS presenting with large vessel occlusive (LVO) disease in previously healthy adolescents recently exposed to SARS-CoV-2 infection. Both patients were subsequently diagnosed with and treated for MIS-C. Here, we discuss the course of their treatments and clinical responses. CONCLUSION: Early recognition and diagnosis of LVO in children with MIS-C is critical in order to make available all treatment options to improve clinical outcomes.
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