Author: Leelawong, Mindy; Mitchell, Stephanie L.; Fowler, Randal C.; Hughes, Scott; Griffith, Marissa P.; Marsh, Jane W.; Harrison, Lee H.; Rakeman, Jennifer L.
Title: SARS-CoV-2 N gene mutations impact detection by clinical molecular diagnostics: Reports in two cities in the United States Cord-id: oi4pmrad Document date: 2021_7_5
ID: oi4pmrad
Snippet: Nasal and nasopharyngeal swab specimens tested by the Cepheid Xpert Xpress SARS-CoV-2 were analyzed by whole-genome sequencing based on impaired detection of the N2 target. Each viral genome had at least one mutation in the N gene, which likely arose independently in the New York City and Pittsburgh study sites.
Document: Nasal and nasopharyngeal swab specimens tested by the Cepheid Xpert Xpress SARS-CoV-2 were analyzed by whole-genome sequencing based on impaired detection of the N2 target. Each viral genome had at least one mutation in the N gene, which likely arose independently in the New York City and Pittsburgh study sites.
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