Author: Jennifer N Rauch; Eric Valois; Sabrina C Solley; Friederike Braig; Ryan S Lach; Naomi J Baxter; Kenneth S Kosik; Carolina Arias; Diego Acosta-Alvear; Maxwell Z Wilson
Title: A Scalable, Easy-to-Deploy, Protocol for Cas13-Based Detection of SARS-CoV-2 Genetic Material Document date: 2020_4_21
ID: hy1xrw6q_16
Snippet: Regular testing may be a key determinant impacting the ability to ascertain foci of infection and reduce false negative rates. Recent studies document that in many individuals, even those with active symptoms, initial tests can be negative, while subsequent tests are positive, and intermittent detection of the virus in samples can also occur [25] [26] [27] [28] . Despite the biochemical reliability of currently-available diagnostics, the initial .....
Document: Regular testing may be a key determinant impacting the ability to ascertain foci of infection and reduce false negative rates. Recent studies document that in many individuals, even those with active symptoms, initial tests can be negative, while subsequent tests are positive, and intermittent detection of the virus in samples can also occur [25] [26] [27] [28] . Despite the biochemical reliability of currently-available diagnostics, the initial quality of a sample and the viral load in the patient can affect the likelihood of a false result. Because of its low costs and ease of use, CREST could be employed for regular testing as well as for disambiguation of results obtained with established methods.
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