Author: Liu, Yanqing
Title: Letter to the Editors: Additional Factors to Consider When Studying Liver Injury Indicators and Mortality in COVIDâ€19 Patients Cord-id: cee8i0r6 Document date: 2020_7_3
ID: cee8i0r6
Snippet: In a recent issue of Hepatology, Lei et al.((1)) conducted a multicenter retrospective cohort study that included 5,771 adult patients with coronavirus disease 2019 (COVIDâ€19) pneumonia in Hubei Province. The purpose of the study was to evaluate the relationships between liver injury indicators (alanine aminotransferase [ALT], aspartate aminotransferase [AST], alkaline phosphatase [ALP], and total bilirubin [TBIL]) and mortality in COVIDâ€19 patients. The authors considered the possibility th
Document: In a recent issue of Hepatology, Lei et al.((1)) conducted a multicenter retrospective cohort study that included 5,771 adult patients with coronavirus disease 2019 (COVIDâ€19) pneumonia in Hubei Province. The purpose of the study was to evaluate the relationships between liver injury indicators (alanine aminotransferase [ALT], aspartate aminotransferase [AST], alkaline phosphatase [ALP], and total bilirubin [TBIL]) and mortality in COVIDâ€19 patients. The authors considered the possibility that elevated liver injury indicators, particularly AST, are strongly associated with mortality risk. However, the association between liver injury indicators and mortality in COVIDâ€19 patients should be interpreted cautiously in light of the following issues.
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