Author: Liangzhong Lim; Amrita Roy; Jianxing Song
Title: Identification of a Zika NS2B-NS3pro pocket susceptible to allosteric inhibition by small molecules including qucertin rich in edible plants Document date: 2016_10_1
ID: gfiukh90_7
Snippet: Recently we identified two small molecules which could amazingly inhibit Zika NS2B-NS3pro in non-competitive mode (19) (20) (21) : one is p-Nitrophenyl-p-guanidino benzoate (pNGB) ( Fig. 1A) , an active site inhibitor for both West Nile and Dengue protease (19) , while another is qucertin (Fig. 1B) , a natural product rich in many edible plant (Fig. 1C) . author/funder. All rights reserved. No reuse allowed without permission......
Document: Recently we identified two small molecules which could amazingly inhibit Zika NS2B-NS3pro in non-competitive mode (19) (20) (21) : one is p-Nitrophenyl-p-guanidino benzoate (pNGB) ( Fig. 1A) , an active site inhibitor for both West Nile and Dengue protease (19) , while another is qucertin (Fig. 1B) , a natural product rich in many edible plant (Fig. 1C) . author/funder. All rights reserved. No reuse allowed without permission.
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