Author: William E. Diehl; Mehmet H. Guney; Pyae Phyo Kyawe; Judith M. White; Massimo Pizzato; Jeremy Luban
Title: Influence of different glycoproteins and of the virion core on SERINC5 antiviral activity Document date: 2019_9_24
ID: 9dybtdi2_15
Snippet: These observations indicate that restriction by SERINC5 is not dictated by how the viral glycoprotein mediates fusion, as fusion mediated by influenza (27) or by RABV (28) occurs in a pH-dependent fashion in the endo-lysosomal compartment, while HIV-1-(29, 30), A-MLV-, M-PMV-and HTLV-1-mediated (31) fusion occurs in a pH-independent manner......
Document: These observations indicate that restriction by SERINC5 is not dictated by how the viral glycoprotein mediates fusion, as fusion mediated by influenza (27) or by RABV (28) occurs in a pH-dependent fashion in the endo-lysosomal compartment, while HIV-1-(29, 30), A-MLV-, M-PMV-and HTLV-1-mediated (31) fusion occurs in a pH-independent manner.
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