Author: Chin-Yi Chu; Xing Qiu; Matthew N. McCall; Lu Wang; Anthony Corbett; Jeanne Holden-Wiltse; Christopher Slaunwhite; Qian Wang; Christopher Anderson; Alex Grier; Steven R. Gill; Gloria S. Pryhuber; Ann R. Falsey; David J. Topham; Mary T. Caserta; Edward E. Walsh; Thomas J Mariani
Title: Insufficiency in airway interferon activation defines clinical severity to infant RSV infection Document date: 2019_5_20
ID: bx49tbui_105
Snippet: Type I/III interferon ligand gene expression over time (day 1-10) was assessed separately in mild and severely affected infants (c.) Shown is the estimated expression level (more red equals higher expression) for individual ligand genes at each day following the onset of clinical symptoms. These data are consistent with an early activation in type I/III interferon pathway activity in mild subjects only. Multiplex ELISA analysis of nasal washes fr.....
Document: Type I/III interferon ligand gene expression over time (day 1-10) was assessed separately in mild and severely affected infants (c.) Shown is the estimated expression level (more red equals higher expression) for individual ligand genes at each day following the onset of clinical symptoms. These data are consistent with an early activation in type I/III interferon pathway activity in mild subjects only. Multiplex ELISA analysis of nasal washes from RSV infected infants (d.) confirms that the production of type I/III interferon ligands is increased in infants with severe clinical symptoms.
Search related documents:
Co phrase search for related documents- clinical symptom and high expression: 1
- clinical symptom and nasal wash: 1
- clinical symptom and severe clinical symptom: 1, 2, 3, 4, 5, 6, 7, 8
- clinical symptom onset and severe clinical symptom: 1
- early activation and expression level: 1, 2
- early activation and gene expression: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
- early activation and high expression: 1
- early activation and type production: 1, 2, 3
- expression level and gene expression: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81
- expression level and high expression: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78
- expression level and infected infant: 1
- expression level and interferon ligand: 1
- expression level and ligand gene: 1, 2, 3
- expression level and pathway activity: 1, 2, 3, 4
- expression level and time gene expression: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
- expression level and type production: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
- gene expression and high expression: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77
- gene expression and infected infant: 1, 2
- gene expression and interferon ligand: 1
Co phrase search for related documents, hyperlinks ordered by date